Hyaluronic Acid

Hyaluronic acid (HA) is a naturally occurring substance found in the body, especially in joint fluid, where it helps lubricate and cushion the joint.

HA injections are most commonly used for osteoarthritis, particularly of the knee, but they may also benefit other joints (hip, shoulder, ankle) where cartilage has worn down.

HA injections aim to restore lubrication, reduce friction, and improve shock absorption in the joint. This can help decrease pain and improve mobility.

Cortisone injections reduce inflammation quickly but are short-term. HA works more gradually by improving joint lubrication and may provide longer-lasting relief in a lot of patients.

Relief is not always immediate. Improvement is often noticed within 2–4 weeks, with maximum benefit sometimes taking 4–8 weeks.

Relief can last from 4 to 6 months, and in some cases up to a year. Response varies by individual and severity of arthritis.

Some HA products are given as a single injection, while others require a series of 3 weekly injections. Your provider will help determine the best option for you.

Side effects are typically mild and temporary and may include pain, swelling or stiffness around the injection site. More significant reactions are uncommon. Your healthcare provider will review the potential risks and benefits with you before proceeding with an injection.

Yes. HA can be used if other treatments haven’t provided enough relief, and it can often be combined with physiotherapy, bracing, or medications.

HA injections may not be recommended for patients with active joint infections or certain allergies (especially to avian products, depending on the brand).

Many extended health insurance plans provide coverage for HA injections, although the amount covered varies by insurance provider and individual plan.

Depending on the insurer, HA may be covered as either a medication or a medical device. Some plans use a PIN (pseudo-DIN) rather than a Drug Identification Number (DIN) when processing coverage.

We recommend checking with your insurance provider in advance to confirm whether your specific HA product is covered and how much your plan will reimburse.

For some patients, HA injections can reduce pain and improve function enough to delay joint replacement surgery, but they do not reverse arthritis.

Avoid strenuous activity for 24–48 hours. Light walking and normal daily activities are usually fine.

No. Although HA injections are commonly used for knee arthritis, they may also be used in other joints, including the hips, shoulders, ankles, thumbs and toes, depending on the condition and your provider’s recommendation.

Certain types of hyaluronic acid may also be used for select tendon conditions. Your provider will determine whether HA is an appropriate treatment option based on your diagnosis and individual needs.

Your provider will consider your age, activity level, arthritis severity, previous treatments, and overall health before recommending HA injections.

Cortisone and HA can be used together when appropriate. In some cases, using them together may provide a combined benefit, with cortisone helping to reduce inflammation more quickly while HA may provide longer-term symptom relief.

Your provider will determine whether using both treatments is appropriate for your condition.

HA is stocked at our clinic so that, when appropriate, your injection can be provided at the time of your appointment without requiring a separate pharmacy visit and return appointment.

As a physician’s office, we are unable to bill the cost of the medication directly to private drug plans. You will be provided with a prescription and receipt that you can submit to your insurance provider for possible reimbursement. Coverage varies by plan and cannot be guaranteed. ASMC is unable to submit these claims on your behalf.